Guanidine Hydrochloride is used as a high purity, GMP Reagent grade product. Guanidine Hydrochloride Buffer is a strong protein denaturant that functions as a chaotropic agent. As a denaturant, it acts to unfold proteins and turn them into their original polypeptide chains. As a chaotropic agent, it breaks down the structure of proteins. Guanidine Hydrochloride Buffer is commonly used in the purification of RNA by dissociating the RNA into its nucleic acids and protein forms. At higher concentrations, Guanidine Hydrochloride Buffer decreases enzyme activity. It is also used to increase the solubility of hydrophobic molecules.
Formula: CH5N3 • HCl
F.W.: 95.53 g/mol
CAS #: 50-01-1
| ANALYSIS | SPECIFICATIONS | ||
|---|---|---|---|
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≤ 5 ppm |
||
|
None Detected None Detected None Detected |
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≤ 0.01% | ||
|
White / Crystals | ||
|
99.5% - 101.0% | ||
|
≤ 0.005% | ||
|
Passes Test | ||
|
≤ 0.2000 a.u. ≤ 0.0300 a.u. ≤ 0.0300 a.u. |
||
|
Meets the Requirements of Test A | ||
|
≤ 0.005% | ||
|
≤ 0.5% |
||
|
184°C – 188°C | ||
|
Passes Test | ||
|
≤ 0.05% max | ||
|
Passes Test | ||
|
NMT 0.3% w/w | ||
|
≤ 0.05% |
Printable Version
Molecular Formula: CH5N3 • HCl
Molecular Weight: 95.53 g/mol
CAS Number: 50-01-1
Three-year expiry from the date of manufacture.
Please refer to the SDS for storage and shipping conditions.
100g, 500g, 1kg, 5kg, 10kg, 25kg, 50kg
American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.