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GMP Biotech Product

GUANIDINE HCL BIOTECH

NF, GMP
Product Code: GHCL-4223

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Price per unit (USD) Price per kilogram (USD)
100g 500g 1kg 2-5kg (1kg ea) 1x5kg 1x10kg
$95 ea. $265 ea. $245 ea. $225 ea. $205 /kg $185 /kg
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QUANTITY
Product Code: GHCL-4223
Intended for Use in Biopharmaceutical & Biotechnological Applications and Products

Guanidine Hydrochloride is used as a high purity, GMP Reagent grade product. Guanidine Hydrochloride Buffer is a strong protein denaturant that functions as a chaotropic agent. As a denaturant, it acts to unfold proteins and turn them into their original polypeptide chains. As a chaotropic agent, it breaks down the structure of proteins. Guanidine Hydrochloride Buffer is commonly used in the purification of RNA by dissociating the RNA into its nucleic acids and protein forms. At higher concentrations, Guanidine Hydrochloride Buffer decreases enzyme activity. It is also used to increase the solubility of hydrophobic molecules.

Formula: CH5N3 • HCl
F.W.: 95.53 g/mol
CAS #: 50-01-1

Product Specifications

ANALYSIS SPECIFICATIONS
Acidity (NF)

< = 0.01%

Appearance and Color  
White Crystals
Assay, Dried Basis (NF)  
99.5 - 101.0%
Enzymes

DNase

Protease

RNase

None Detected

None Detected

None Detected

Identification A, IR (NF)  
Conforms to Reference Standard
Identification B, Absorbance (6M) (NF)

230 nm

260 nm

275 nm

< = 0.2000 a.u.

< = 0.0300 a.u.

< = 0.0300 a.u.

Identification C, Chloride (NF)  
Passes Test
Limit of Nitrate (NF)  
< = 50 ppm
Loss on Drying (NF)  
< = 0.5%
Melting Range (NF)  
184°C – 188°C
pH (6M)  

4.5 - 6.0

Residue on Ignition (NF)  
< = 0.05%
Solubility (6M)  
Passes Test
Sulfate (NF) < = 50 ppm
Trace Metals Aluminum (Al)
Arsenic (As)
Barium (Ba)
Bismuth (Bi)
Calcium (Ca)
Cadmium (Cd)
Cobalt (Co)
Chromium (Cr)
Copper (Cu)
Iron (Fe)
Potassium (K)
Lithium (Li)
Magnesium (Mg)
Manganese (Mn)
Molybdenum (Mo)
Sodium (Na)
Nickel (Ni)
Lead (Pb)
Strontium (Sr)
Zinc (Zn)
< = 5 ppm
< = 5 ppm
< = 5 ppm
< = 5 ppm
< = 10 ppm
< = 5 ppm
< = 5 ppm
< = 5 ppm
< = 5 ppm
< = 5 ppm
< = 50 ppm
< = 5 ppm
< = 5 ppm
< = 5 ppm
< = 5 ppm
< = 150 ppm
< = 5 ppm
< = 5 ppm
< = 5 ppm
< = 5 ppm
Water, KF  
< = 0.3%
Water Insoluble Substances (NF)  
< = 0.05%

 

Printable Version

General Product Description:

  • Molecular Formula: CH5N3 • HCl
  • Molecular Weight: 95.53 g/mol
  • CAS Number: 50-01-1
  • Appears as a white crystalline product
  • Manufactured in accordance with IPEC
  • Manufactured in an enzyme free, hormone free and animal free environment
  • Contains no known major food allergens (as defined by FDA and WHO)
  • The final product nor its raw materials are not derived from nor come into contact with animals, animal parts, animal products, and/or animal byproducts or derivatives.
  • Is not subject to genetic modification
  • Synonyms: Guanidine Monohydrochloride, Guanidinium Chloride, Guanidinium Hydrochloride Buffer.

Shelf Life Policy:

Each Certificate of Analysis (CoA) will contain a 2-year retest date supported by a 3-year ICH Q1 Stability Study (if one is completed).

Storage and Shipping Conditions:

Please refer to the SDS for storage and shipping conditions.

Package Sizes:

100g, 500g, 1kg, 5kg, 10kg, 25kg, 50kg

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.