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GMP Biotech Product

GUANIDINE THIOCYANATE BIOTECH

GMP

COAs Spec Sheet

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Product Code: GTHI-4221
Intended for Use in Biopharmaceutical & Biotechnological Applications and Products

Guanidine Thiocyanate is used as a high purity, GMP Reagent grade product. Guanidine Thiocyanate is a chaotropic agent. As one of the strongest protein denaturants, it inactivates nucleases more than twice as fast as Guanidine Hydrochloride. Guanidine Thiocyanate is preferred for the purification of RNA because it dissociates the RNA into its nucleic acids and protein forms. Higher molarity solutions of Guanidine Thiocyanate irreversibly inactivate RNase. Guanidine Thiocyanate causes proteins to dissolve readily, thus disintegrating cellular structures.

Formula: C2H6N4S
F.W.: 118.16 g/mol
CAS #: 593-84-0

Product Specifications

ANALYSIS SPECIFICATIONS
Trace Metals

Arsenic (As)

Aluminum (AL)

Barium (Ba)

Bismuth (Bi)

Calcium (Ca)

Cadmium (Cd)

Chromium (Cr)

Cobalt (Co)

Copper (Cu)

Iron (Fe)

Potassium (K)

Lead (Pb)

Lithium (Li)

Magnesium (Mg)

Manganese (Mn)

Molybdenum (Mo)

Sodium (Na)

Nickel (Ni)

Strontium (Sr)

Zinc (Zn)

≤ 5 ppm

≤ 5 ppm

≤ 5 ppm

≤ 5 ppm

≤ 10 ppm

≤ 5 ppm

≤ 5 ppm

≤ 5 ppm

≤ 5 ppm

≤ 5 ppm

≤ 50 ppm

≤ 5 ppm

≤ 5 ppm

≤ 5 ppm

≤ 5 ppm

≤ 5 ppm

≤ 5000 ppm

≤ 5 ppm

≤ 5 ppm

≤ 5 ppm

Enzymes

DNase

Protease

RNase

None Detected

None Detected

None Detected

Absorbance

280 nm

300 nm

340 nm

0.300 a.u. maximum

0.050 a.u. maximum

0.030 a.u. maximum

Appearance and Color  
White / Crystals
Assay  
99.0% - 101.0%
Identification (IR)  
Passes Test
Loss on Drying  
0.5% maximum
pH (5% Solution)  
5.0 - 7.0
Melting Point  
115-121°C
Sulfated Ash  
≤ 0.5%
Infrared Spectrum  
Conforms to Structure
Sulfate (SO4)  
≤ 50 mg/kg

 

Printable Version

General Product Description:

  • Molecular Formula: C2H6N4S
  • Molecular Weight: 118.16 g/mol
  • CAS Number: 593-84-0

Guanidine Thiocyanate Biotech:

  • Appears as a white crystalline product.
  • Is manufactured under an ICH-Q7 Quality Managed cGMP System
  • Manufactured in an enzyme free, hormone free and animal free environment
  • Has no known major food allergens (as defined by FDA and WHO)
  • The final product nor its raw materials are not derived from nor come into contact with animals, animal parts, animal products, and/or animal byproducts or derivatives.
  • Is not subject to genetic modification
  • Synonyms: Guanidine Hydro Thiocyanate, Guanidine Isothiocyanate, Guanidine Mono Thiocyanate.

Shelf Life Policy:

Three-year expiry from the date of manufacture.

Storage and Shipping Conditions:

Please refer to the SDS for storage and shipping conditions.

Package Size:

100g, 500g, 1kg, 5kg, 10kg, 25kg, 50kg

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.