banner
GMP Buffer

GMP Manufactured Process Chemical

MOPS Free Acid

GMP Grade

Minimum Order Quantity: 250kg Lead Time (if no stock): 3-6 months
COAs Spec Sheet

Product Inquiry

Location of company
Self-use or resale *
If resale please fill out the following information
Intended application *
Intended end use *
Intended Use *
Application *
Package and Size *
Product Code: MOPS-4220 | Previously: MP4220
Intended For Use In Pharmaceutical GMP Processes

MOPS is a zwitterionic buffer used as a running buffer for denaturing gel electrophoresis and as a buffering agent in many biological and biochemical applications. MOPS interferes with the Folin protein assay and partially decomposes when autoclaved in the presence of glucose. MOPS can be used as a Good’s buffer because it has low UV absorptivity, minimal reactivity, stable pH and is soluble in water.

CAS #: 1132-61-2
Formula: C7H15NO4S
Sol. In H2O (g/L): 980
F.W.: 209.26 g/mol
pH @ 20°C: 3.0 - 4.5
Useful pH: 6.5 - 7.9
pKa @ 20˚C: 7.2

Product Specifications

ANALYSIS SPECIFICATIONS
 

250 nm

Absorbance (0.1M)

260 nm

 

280 nm

0.020 a.u. maximum

0.020 a.u. maximum.

0.020 a.u. maximum

Appearance and Color  
White / Crystals
Assay  
99.5% min.
Chloride  
0.005% max.
Enzymes

DNase

RNase

Protease

None Detected
None Detected
None Detected

Identification (IR)  
Passes Test
Karl Fischer Water  
0.1% max.
Loss on Drying  
1.0% max.
pH (1% solution)  
3.0-4.5

pH (2.5M)

 
2.5-4.5
pKa  

7.0-7.5

Residue on Ignition  
0.1% max.
Solubility (5%)  
Passes Test
Sulfate  
0.005% max.
Trace Metals

Arsenic (As)
Copper (Cu)
Iron (Fe)
Lead (Pb)

5 ppm max.
5 ppm max.
5 ppm max.
5 ppm max.

 

Printable Version

General Product Description:

  • The manufacturing of Bio Pharma Grade MOPS MOPS-4220 is performed at BioSpectra’s Stroudsburg, PA facility and
    is conducted in a dedicated processing area using only dedicated equipment.
  • MOPS is a White Crystalline product.
  • Molecular Formula: C7H15NO4S
  • Molecular Weight: 209.26 g/mol.
  • CAS Number: 1132-61-2.
  • There are no known major food allergens (as defined by FDA and WHO) in the manufacture of this product.
  • BioSpectra certifies that all MOPS MOPS-4220 manufactured at BioSpectra and its raw materials are not derived from
    or come in contact with animal parts, products, and/or byproducts.
  • MOPS manufactured at BioSpectra and any raw materials used in the manufacture of MOPS at BioSpectra are not subject to genetic modification.
  • Synonyms: 3-(N-Morpholino)propanesulfonic acid, 4-Morpholinepropanesulfonic acid.

GMP Compliance:

Bio Pharma Grade MOPS, Free Acid MOPS-4220 is suitable for use as a process chemical. It is manufactured in accordance with the IPEC-PQG Joint Good Manufacturing Practice Guide. This grade of MOPS, Free Acid is not suitable to be used as an Active Pharmaceutical Ingredient, Drug, Drug Product or Household Item.

Retest Date:

The recommended retest period for MOPS is two years from the date of manufacture.

Storage and Shipping Conditions:

Ship and Store in ambient temperature.

Package Sizes:

10kg, 25kg and 50kg pails.

Bulk GMP Fine Chemicals exclusively manufactured in North America

American Manufactured - FDA Registered GMP Facilities: Parenteral Excipients, GMP Small Molecule Intermediates, GMP Biological Buffers, Parenteral Carbohydrates, GMP Chlorinated Amino Acids, GMP Solutions in Sterile Single Use Packaging and other Reagent & GMP Fine Chemicals.